Association Between Thyroid Disorders and Colorectal Cancer Risk in Adult Patients in Taiwan.

ABSTRACT:

Importance

Thyroid hormones have been shown to affect several important pathways in cancer development, including colorectal cancer (CRC). Clinical studies examining the association between thyroid disorders and colorectal cancer have conflicting results and have predominantly involved white populations.

Objective

To determine if a diagnosis of hyperthyroidism or hypothyroidism is associated with the risk of developing colorectal cancer in an East Asian population.

Design, setting, and participants

This nationwide population-based case-control study was conducted from April 27, 2018, to November 8, 2018, using the Taiwanese National Health Insurance Research Database. Participants were adults (n = 139 426) either with a new diagnosis (between 2008 and 2013) of primary

SUBMITTER: L'Heureux A 

PROVIDER: S-EPMC6537921 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature