Changes in plasma phospholipid fatty acid profiles over 13 years and correlates of change: European Prospective Investigation into Cancer and Nutrition-Norfolk Study.

ABSTRACT:

Background

Little is known about changes in blood fatty acid compositions over time and the correlates of any changes in a general population.

Objective

The aim of this study was to estimate changes in 27 individual plasma phospholipid fatty acids and fatty acid groups over time, and to identify potential correlates of these changes.

Methods

Plasma phospholipid fatty acids were profiled at 3 time-points (1993-1997, 1998-2000, 2004-2011) among 722 participants in the European Prospective Investigation into Cancer and Nutrition-Norfolk Study, UK. Linear regression models were used to estimate both 1) mean changes over time in 27 individual fatty acids and 8 prespecified fatty acid groups and 2) associations of changes in dietary and lifestyle factors with changes in the

SUBMITTER: Zheng JS 

PROVIDER: S-EPMC6537938 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature