Database analysis of the risk factors of bisphosphonate-related osteonecrosis of the jaw in Hungarian patients.

ABSTRACT:

Objective

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare but serious side effect of bisphosphonates (BPs). Since this disease has no independent code in either of the diseases' or in the medical procedures' classifications, it is hard to estimate how many BP patients are affected.

Design

A retrospective observational epidemiological registry-based study was carried out, using the data of the national service of Hungary on the incidence of BRONJ and related factors.

Setting

A data analysis was performed, which is relevant for the whole Hungarian population from 2010 to 2014. The socioeconomic and medication data of 236 207 BP patients were analysed, and a method was worked out to define BRONJ patients from the Hungarian BP population.

Primary and

SUBMITTER: Veszelyne Kotan E 

PROVIDER: S-EPMC6537976 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature