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Establishing a core outcome set for treatment of uncomplicated appendicitis in children: study protocol for an international Delphi survey.


ABSTRACT:

Introduction

Appendicitis is a global disease affecting roughly 1 in every 12 people in the world, with the highest incidence between ages 10 and 19 years. To date, a wide variety of health outcomes have been reported in randomised controlled trials and meta-analyses evaluating treatments for appendicitis. This is especially the case in studies comparing non-operative treatment with operative treatment. A set of standard outcomes, to be reported in all future trials, is needed to allow for adequate comparison and interpretation of clinical trial results and to make data pooling possible. This protocol describes the development of such a global core outcome set (COS) to allow unified reporting of treatment interventions in children with acute uncomplicated appendicitis.

Methods a

SUBMITTER: Knaapen M 

PROVIDER: S-EPMC6538019 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature