Reduced cortical folding in multi-modal vestibular regions in persistent postural perceptual dizziness.

ABSTRACT: Persistent postural perceptual dizziness (PPPD) is a common functional vestibular disorder that is triggered and sustained by a complex interaction between physiological and psychological factors affecting spatial orientation and postural control. Past functional neuroimaging research and one recent structural (i.e., voxel-based morphometry-VBM) study have identified alterations in vestibular, visuo-spatial, and limbic brain regions in patients with PPPD and anxiety-prone normal individuals. However, no-one thus far has employed surface based morphometry (SBM) to explore whether cortical morphology in patients with PPPD differs from that of healthy people. We calculated SBM measures from structural MR images in 15 patients with PPPD and compared them to those from 15 healthy controls match

SUBMITTER: Nigro S 

PROVIDER: S-EPMC6538588 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature