Nutritional counseling with or without mobile health technology: a randomized open-label standard-of-care-controlled trial in ALS.

ABSTRACT:

Background

Nutritional status is an important prognostic factor in Amyotrophic Lateral Sclerosis (ALS). We wished to study the safety, tolerability and efficacy of nutritional counseling with or without an mHealth application to maintain or increase body weight in ALS, compared to standard care.

Methods

In this randomized open-label, standard-of-care-controlled, single-center clinical trial, we randomly assigned adults with ALS to one of three nutritional interventions: counseling by their physician or nurse ("standard care"), counseling by a registered dietitian (RD) ("in-person"), or counseling supported by a mHealth app ("mHealth"). Both intervention arms received tailored nutrition recommendations and recorded dietary intake and weight biweekly (mHealth) or monthly (in-p

SUBMITTER: Wills AM 

PROVIDER: S-EPMC6540456 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature