Prognostic value of lipid profiles after radical prostatectomy: a systematic review and meta-analysis.

ABSTRACT:

Background

Lipid profiles are believed to play an important role in the tumorigenesis and progression of prostate cancer (PCa), but research combining those data is lacking. Therefore, this meta-analysis aims to assess the prognostic role of lipid profiles after RP.

Method

We systematically searched PubMed, Embase, and Cochrane Library Central Register of Controlled Trials for articles evaluating association between lipid profiles and prognosis after RP. Odds ratio (OR) and hazard ratio (HR) of lipid profiles for advanced pathological tumor features and biochemical recurrence (BCR) were extracted and pooled OR and HR were calculated. Newcastle-Ottawa scale was used for study quality assessment and funnel plot was used for evaluating publication bias.

Results

Twelve ar

SUBMITTER: Zheng X 

PROVIDER: S-EPMC6540553 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature