Ontology highlight
ABSTRACT:
SUBMITTER: Wamsley B
PROVIDER: S-EPMC6541232 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Neuron 20181011 4
Cortical interneurons display a remarkable diversity in their morphology, physiological properties, and connectivity. Elucidating the molecular determinants underlying this heterogeneity is essential for understanding interneuron development and function. We discovered that alternative splicing differentially regulates the integration of somatostatin- and parvalbumin-expressing interneurons into nascent cortical circuits through the cell-type-specific tailoring of mRNAs. Specifically, we identif ...[more]