MRI predicts intracranial hemorrhage in patients who receive long-term oral anticoagulation.

ABSTRACT:

Objective

We tested the hypothesis that the risk of intracranial hemorrhage (ICH) in patients with cardioembolic ischemic stroke who are treated with oral anticoagulants (OAs) can be predicted by evaluating surrogate markers of hemorrhagic-prone cerebral angiopathies using a baseline MRI.

Methods

Patients were participants in a multicenter and prospective observational study. They were older than 64 years, had a recent cardioembolic ischemic stroke, and were new users of OAs. They underwent a baseline MRI analysis to evaluate microbleeds, white matter hyperintensities, and cortical superficial siderosis. We collected demographic variables, clinical characteristics, risk scores, and therapeutic data. The primary endpoint was ICH that occurred during follow-up. We performed bi

SUBMITTER: Marti-Fabregas J 

PROVIDER: S-EPMC6541433 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature