Simulation of Fast-Scan Nanogap Voltammetry at Double-Cylinder Ultramicroelectrodes.

ABSTRACT: High temporal resolution of fast-scan cyclic voltammetry (FSCV) is widely appreciated in fundamental and applied electrochemistry to quantitatively investigate rapid dynamics of electron transfer and neurotransmission using ultramicroelectrodes (UMEs). Faster potential scan, however, linearly increases the background current, which must be subtracted for quantitative FSCV. Herein, we numerically simulate fast-scan nanogap voltammetry (FSNV) for quantitative detection of diffusing redox species under quasi-steady states without the need of background subtraction while maintaining high temporal resolution of transient FSCV. These advantages of FSNV originate from the use of a parallel pair of cylindrical UMEs with nanometer-wide separation in contrast to FSCV with single UMEs. In FSNV, diffu

SUBMITTER: Pathirathna P 

PROVIDER: S-EPMC6541457 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature