Risk factors and outcomes of Clostridium difficile infection in hospitalized patients.

ABSTRACT:

Background

The aim of this study was to identify risk factors for Clostridium difficile infection (CDI) and its attributable mortality and to propose methods to prevent CDI and improve patients' outcomes.

Methods

CDI was defined as diarrheal patients with stool samples that were positive for C. difficile toxin. Clinical presentations of all patients with CDI and two times as many age- and sex-matched culture-negative controls at the Chang Gung Memorial Hospital in 2014 were identified and compared by multivariate, nonparametric, and Kaplan-Meier survival analysis.

Results

There were no significant differences in ages, sex, or Charlson comorbidity indexes between the CDI group (n = 42) and the control group (n = 86). The multivariate analysis indicated that underlying

SUBMITTER: Lee HY 

PROVIDER: S-EPMC6541878 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature