Effect of prior cancer on survival outcomes for patients with pancreatic adenocarcinoma: a propensity score analysis.

ABSTRACT:

Background

With the increase in cancer survivors, more pancreatic ductal adenocarcinomas (PDACs) are developing as second primary cancers. Whether a prior cancer has an inferior impact on survival outcomes in patients with PDAC remains unknown, and the validity of criteria used to exclude patients with prior cancers in clinical trials needs to be determined. The aim of this study was to evaluate the prognostic factors and assess the survival impact of a prior cancer in patients with second primary PDAC.

Methods

Patients with PDAC were retrospectively selected from the Surveillance, Epidemiology, and End Results (SEER) database. Overall survival (OS) and cancer-specific mortality rates were compared between patients with and those without prior cancer.

Results

The data

SUBMITTER: He C 

PROVIDER: S-EPMC6542019 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature