Physical exercise for prevention of dementia (EPD) study: background, design and methods.

ABSTRACT:

Background

Several observational studies have shown that exercise reduces the risk of cognitive decline; however, evidences from long-term, well-conducted, randomized controlled trials are scanty. The principal aim of this study is to verify whether a long-term program of multimodal supervised exercise improves the cognitive function and/or reduces the rate of cognitive decline in older adults at different degrees of risk for dementia.

Methods/design

EPD is a parallel group, double-blind, randomized controlled trial. Community-dwelling volunteers aged 50 years or more are being recruited from different community centers and screened for eligibility. Enrolled subjects are being divided in 3 groups: a) without subjective or objective cognitive impairment, b) with subjective me

SUBMITTER: Iuliano E 

PROVIDER: S-EPMC6542067 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature