Single versus double-unit transfusion: Safety and efficacy for patients with hematologic malignancies.

ABSTRACT:

Objectives

Although hemoglobin thresholds for red blood cell (RBC) transfusion have decreased, double-unit RBC transfusion practices persist. We studied the effects switching from predominantly double-unit to single-unit RBC transfusions had on utilization and clinical outcomes for malignant hematology patients.

Methods

Retrospective chart review compared malignant hematology patients before and after implementing single-unit RBC transfusion policy. Hemoglobin threshold was 8.0 g/dL for both groups. RBC utilization metrics included number of RBC units transfused, RBC units transfused per admission, and number of transfusion episodes. Clinical outcomes included length of stay, 30-day mortality, and outpatient RBC transfusion 30-days post-discharge.

Results

Baseline hem

SUBMITTER: Bowman Z 

PROVIDER: S-EPMC6542263 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature