Inflammatory Bowel Disease and the Risk of Prostate Cancer.

ABSTRACT:

Background

There are limited data examining the risk of prostate cancer (PCa) in patients with inflammatory bowel disease (IBD).

Objective

To compare the incidence of PCa between men with and those without IBD.

Design, setting, and participants

This was a retrospective, matched-cohort study involving a single academic medical center and conducted from 1996 to 2017. Male patients with IBD (cases=1033) were randomly matched 1:9 by age and race to men without IBD (controls=9306). All patients had undergone at least one prostate-specific antigen (PSA) screening test.

Outcome measurements and statistical analysis

Kaplan-Meier and multivariable Cox proportional hazard models, stratified by age and race, evaluated the relationship between IBD and the incidence of any

SUBMITTER: Burns JA 

PROVIDER: S-EPMC6542355 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature