Model-Interpolated Gating for Magnetic Resonance Image-Guided Radiation Therapy.

ABSTRACT:

Purpose

To develop and validate a technique for radiation therapy gating using slow (≤1 frame per second) magnetic resonance imaging (MRI) and a motion model. Proposed uses of the technique include radiation therapy gating using T2-weighted images and conducting additional imaging studies during gated treatments.

Methods and materials

The technique uses a physiologically guided breathing motion model to interpolate deformed target position between 2-dimensional (2D) MRI images acquired every 1 to 3 seconds. The model is parameterized by a 1-dimensional respiratory bellows surrogate and is continuously updated with the most recently acquired 2D images. A phantom and 8 volunteers were imaged with a 0.35T MRI-guided radiation therapy system. A balanced steady-state free precess

SUBMITTER: Ginn JS 

PROVIDER: S-EPMC6542358 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature