Multimodal Imaging and Spatial Analysis of Ebola Retinal Lesions in 14 Survivors of Ebola Virus Disease.

ABSTRACT:

Importance

Differentiation between Ebola retinal lesions and other retinal pathologies in West Africa is important, and the pathogenesis of Ebola retinal disease remains poorly understood.

Objective

To describe the appearance of Ebola virus disease (EVD) retinal lesions using multimodal imaging to enable inferences on potential pathogenesis.

Design, setting, and participants

This prospective case series study was carried out at 34 Military Hospital in Freetown, Sierra Leone. Ophthalmological images were analyzed from 14 consecutively identified survivors of EVD of Sierra Leonean origin who had identified Ebola retinal lesions.

Main outcomes and measures

Multimodal imaging findings including ultra-widefield scanning laser ophthalmoscopy, fundus autofluorescence,

SUBMITTER: Steptoe PJ 

PROVIDER: S-EPMC6542654 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature