Vital exhaustion and sudden cardiac death in the Atherosclerosis Risk in Communities Study.

ABSTRACT:

Objective

Vital exhaustion (VE), a construct defined as lack of energy, increased fatigue and irritability, and feelings of demoralisation, has been associated with cardiovascular events. We sought to examine the relation between VE and sudden cardiac death (SCD) in the Atherosclerosis Risk in Communities (ARIC) Study.

Methods

The ARIC Study is a predominately biracial cohort of men and women, aged 45-64 at baseline, initiated in 1987 through random sampling in four US communities. VE was measured using the Maastricht questionnaire between 1990 and 1992 among 13 923 individuals. Cox proportional hazards models were used to examine the hazard of out-of-hospital SCD across tertiles of VE scores.

Results

Through 2012, 457 SCD cases, defined as a sudden pulseless conditio

SUBMITTER: Bogle BM 

PROVIDER: S-EPMC6542734 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature