Production of 3-Hydroxypropanoic Acid From Glycerol by Metabolically Engineered Bacteria.

ABSTRACT: 3-hydroxypropanoic acid (3-HP) is a valuable platform chemical with a high demand in the global market. 3-HP can be produced from various renewable resources. It is used as a precursor in industrial production of a number of chemicals, such as acrylic acid and its many derivatives. In its polymerized form, 3-HP can be used in bioplastic production. Several microbes naturally possess the biosynthetic pathways for production of 3-HP, and a number of these pathways have been introduced in some widely used cell factories, such as Escherichia coli and Saccharomyces cerevisiae. Latest advances in the field of metabolic engineering and synthetic biology have led to more efficient methods for bio-production of 3-HP. These include new approaches for introducing heterologous pathways,

SUBMITTER: Jers C 

PROVIDER: S-EPMC6542942 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature