Gender Specific Differences in Prevalence and Risk Factors for Gastro-Esophageal Reflux Disease.

ABSTRACT:

Background

Gender-related factors might play an important role in the development of reflux esophagitis (RE) and symptomatic gastro-esophageal reflux disease (GERD). We aimed to evaluate the prevalence and risk factors for RE and symptomatic GERD and determine whether gender specific differences exist.

Methods

This study was conducted on a health cohort consisting of 10,158 participants who underwent comprehensive health screening. Lifestyles and gastrointestinal symptoms were investigated using a self-reported structured questionnaire. Questionnaires about menstrual status were added for the women.

Results

The prevalence of RE in men was significantly higher than that in women (10.6% vs. 2.0%, P < 0.001); however, symptomatic GERD showed predominance in women

SUBMITTER: Kim SY 

PROVIDER: S-EPMC6543060 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature