Bacterial Cholangitis in Autosomal Dominant Polycystic Kidney and Liver Disease.

ABSTRACT:

Objective

To describe first episodes of bacterial cholangitis complicating autosomal dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver disease (ADPLD) and to identify risk factors for cholangitis episodes among patients with ADPKD-associated polycystic liver disease (PLD).

Patients and methods

We searched the electronic medical records at our tertiary referral center for episodes of cholangitis in patients with ADPKD or ADPLD from January 1, 1996, through June 30, 2017. Cases were categorized as suspected or definite cholangitis by expert review. Clinical, laboratory, and radiologic data were manually abstracted. A nested case-control study was conducted to investigate risk factors for cholangitis in patients with ADPKD.

Results

We ide

SUBMITTER: Martin WP 

PROVIDER: S-EPMC6543502 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature