Models with indirect genetic effects depending on group sizes: a simulation study assessing the precision of the estimates of the dilution parameter.

ABSTRACT:

Background

In settings with social interactions, the phenotype of an individual is affected by the direct genetic effect (DGE) of the individual itself and by indirect genetic effects (IGE) of its group mates. In the presence of IGE, heritable variance and response to selection depend on size of the interaction group (group size), which can be modelled via a 'dilution' parameter (d) that measures the magnitude of IGE as a function of group size. However, little is known about the estimability of d and the precision of its estimate. Our aim was to investigate how precisely d can be estimated and what determines this precision.

Methods

We simulated data with different group sizes and estimated d using a mixed model that included IGE and d. Schemes included various average grou

SUBMITTER: Heidaritabar M 

PROVIDER: S-EPMC6543592 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature