Association of circulating BMP9 with coronary heart disease and hypertension in Chinese populations.

ABSTRACT:

Background

Bone morphogenetic protein9 (BMP9) has been reported to have a role in vascular development. However, there is still a lack of information regarding the association between circulating BMP9 levels and cardiovascular disease in humans. The goal of this study is to measure circulating BMP9 concentrations in patients with essential hypertension (HTN), coronary heart disease (CHD) and HTN + CHD, and evaluates the relationship between circulating BMP9 and these cardiovascular diseases.

Methods

A total of 417 individuals were recruited for this cross-sectional study from June 2015 to December 2017. These subjects were screened for HTN and CHD. Circulating BMP9 concentrations were measured by ELISA.

Results

Circulating BMP9 concentrations were significantly low in

SUBMITTER: Liu R 

PROVIDER: S-EPMC6543594 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature