Functional analysis of lncRNAs based on competitive endogenous RNA in tongue squamous cell carcinoma.

ABSTRACT:

Backround

Tongue squamous cell carcinoma (TSCC) is the most common malignant tumor in the oral cavity. An increasing number of studies have suggested that long noncoding RNA (lncRNA) plays an important role in the biological process of disease and is closely related to the occurrence and development of disease, including TSCC. Although many lncRNAs have been discovered, there remains a lack of research on the function and mechanism of lncRNAs. To better understand the clinical role and biological function of lncRNAs in TSCC, we conducted this study.

Methods

In this study, 162 tongue samples, including 147 TSCC samples and 15 normal control samples, were investigated and downloaded from The Cancer Genome Atlas (TCGA). We constructed a competitive endogenous RNA (ceRNA) regula

SUBMITTER: Song Y 

PROVIDER: S-EPMC6544013 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature