Acute kidney injury after out of hospital pediatric cardiac arrest.

ABSTRACT:

Importance

Many children with return of spontaneous circulation (ROSC) following cardiac arrest (CA) experience acute kidney injury (AKI). The impact of therapeutic hypothermia on the epidemiology of post-CA AKI in children has not been fully investigated.

Objective

The study aims were to: 1) describe the prevalence of severe AKI in comatose children following out-of-hospital CA (OHCA), 2) identify risk factors for severe AKI, 3) evaluate the impact of therapeutic hypothermia on the prevalence of severe AKI, and 4) evaluate the association of severe AKI with survival and functional outcomes.

Design

A post hoc secondary analysis of data from the Therapeutic Hypothermia after Pediatric Cardiac Arrest Out-of-Hospital (THAPCA-OH) trial.

Setting

Thirty-six pediatric

SUBMITTER: Cornell TT 

PROVIDER: S-EPMC6544025 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature