The association between lifestyle factors and Parkinson's disease progression and mortality.

ABSTRACT:

Background

Lifestyle factors may contribute to the development of Parkinson's disease, but little is known about factors that influence progression. The objective of the current study was to examine whether caffeine or alcohol consumption, physical activity, or cigarette smoking is associated with progression and survival among PD patients.

Methods

We assessed lifelong coffee, tea, and alcohol consumption, smoking, and physical activity in a prospective community-based cohort (n = 360). All patients were passively followed for mortality (2001-2016); 244 were actively followed on average ± SD 5.3 ± 2.1 years (2007-2014). Movement disorder specialists repeatedly assessed motor function (Hoehn & Yahr) and cognition (Mini-Mental State Exam). We used Cox proportional hazards mode

SUBMITTER: Paul KC 

PROVIDER: S-EPMC6544143 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature