The relationship between ECG predictors of cardiac resynchronization therapy benefit.

ABSTRACT:

Introduction

Cardiac resynchronization therapy (CRT) is an effective treatment that reduces mortality and improves cardiac function in patients with left bundle branch block (LBBB). However, about 30% of patients passing the current criteria do not benefit or benefit only a little from CRT. Three predictors of benefit based on different ECG properties were compared: 1) "strict" left bundle branch block classification (SLBBB); 2) QRS area; 3) ventricular electrical delay (VED) which defines the septal-lateral conduction delay. These predictors have never been analyzed concurrently. We analyzed the relationship between them on a subset of 602 records from the MADIT-CRT trial.

Methods & results

SLBBB classification was performed by two experts; QRS area and VED were computed fu

SUBMITTER: Halamek J 

PROVIDER: S-EPMC6544221 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature