Automated fiber tract reconstruction for surgery planning: Extensive validation in language-related white matter tracts.

ABSTRACT: Diffusion MRI and tractography hold great potential for surgery planning, especially to preserve eloquent white matter during resections. However, fiber tract reconstruction requires an expert with detailed understanding of neuroanatomy. Several automated approaches have been proposed, using different strategies to reconstruct the white matter tracts in a supervised fashion. However, validation is often limited to comparison with manual delineation by overlap-based measures, which is limited in characterizing morphological and topological differences. In this work, we set up a fully automated pipeline based on anatomical criteria that does not require manual intervention, taking advantage of atlas-based criteria and advanced acquisition protocols available on clinical-grade MRI scanners. T

SUBMITTER: Mancini M 

PROVIDER: S-EPMC6545442 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature