Associations between human milk oligosaccharides and infant body composition in the first 6 mo of life.

ABSTRACT:

Background

Evidence linking breastfeeding to reduced risk of developing childhood obesity is inconclusive, yet previous studies have not considered variation in specific components of breast milk that may affect early development.

Objective

We examined whether differences in the composition of human milk oligosaccharides (HMOs) correlate with infant growth and body composition at 1 and 6 mo of age.

Design

Twenty-five mother-infant dyads were recruited from the University Hospital at the University of Oklahoma Health Sciences Center. Infants were breastfed for 6 mo. Breast-milk and infant measures were obtained at 1 and 6 mo of infant age. HMO composition was analyzed by high-pressure liquid chromatography, and infant growth (length and weight) and body composition (pe

SUBMITTER: Alderete TL 

PROVIDER: S-EPMC6546222 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature