A deformation-based approach for characterizing brain asymmetries at different spatial scales of resolution.

ABSTRACT:

Background

Structural cerebral asymmetries are hypothesized to provide an architectural foundation for functional asymmetries and behavioral lateralities. Studies of structural asymmetries typically focus on gray matter measures that are influenced by gross deformation fields used for normalization, and thus characterize a combination of different morphologic influences on structural asymmetries.

New method

A deformation-based morphometry approach was developed to characterize structural asymmetries at different spatial scales of resolution, which can provide relatively more specific inference about the morphologic reason(s) for structural asymmetries, using a dataset of 347 typically developing children (7.00-12.92 years).

Results

Significant structural asymmetries w

SUBMITTER: Eckert MA 

PROVIDER: S-EPMC6546427 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature