Evaluation of the Diagnostic Stability of the Early Autism Spectrum Disorder Phenotype in the General Population Starting at 12 Months.

ABSTRACT:

Importance

Universal early screening for autism spectrum disorder (ASD) in primary care is becoming increasingly common and is believed to be a pivotal step toward early treatment. However, the diagnostic stability of ASD in large cohorts from the general population, particularly in those younger than 18 months, is unknown. Changes in the phenotypic expression of ASD across early development compared with toddlers with other delays are also unknown.

Objectives

To examine the diagnostic stability of ASD in a large cohort of toddlers starting at 12 months of age and to compare this stability with that of toddlers with other disorders, such as developmental delay.

Design, setting, and participants

In this prospective cohort study performed from January 1, 2006, to Decemb

SUBMITTER: Pierce K 

PROVIDER: S-EPMC6547081 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature