Burden of Environmental Adversity Associated With Psychopathology, Maturation, and Brain Behavior Parameters in Youths.

ABSTRACT:

Importance

Low socioeconomic status (L-SES) and the experience of traumatic stressful events (TSEs) are environmental factors implicated in behavioral deficits, abnormalities in brain development, and accelerated maturation. However, the relative contribution of these environmental factors is understudied.

Objective

To compare the association of L-SES and TSEs with psychopathology, puberty, neurocognition, and multimodal neuroimaging parameters in brain maturation.

Design, setting, and participants

The Philadelphia Neurodevelopmental Cohort is a community-based study examining psychopathology, neurocognition, and neuroimaging among participants recruited through the Children's Hospital of Philadelphia pediatric network. Participants are youths aged 8 to 21 years at en

SUBMITTER: Gur RE 

PROVIDER: S-EPMC6547104 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature