Association of Preterm Birth With Risk of Ischemic Heart Disease in Adulthood.

ABSTRACT:

Importance

Preterm birth has previously been associated with increased risks of hypertension and diabetes, but not ischemic heart disease (IHD), in adulthood. The reasons for this lack of association with IHD despite associations with its risk factors have been elusive, but may be associated with methodologic issues, such as survivor bias, in prior studies.

Objective

To determine whether preterm birth is associated with an increased risk of IHD in adulthood in a large population-based cohort.

Design, setting, and participants

This national, population-based cohort study included all 2 141 709 persons who were born as singleton live births in Sweden during 1973 to 1994. The data were analyzed in September 2018.

Exposures

Gestational age at birth, identified from

SUBMITTER: Crump C 

PROVIDER: S-EPMC6547251 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature