Orthostatic intolerance in chronic fatigue syndrome.

ABSTRACT:

Background

Orthostatic intolerance (OI) is a significant problem for those with chronic fatigue syndrome (CFS). We aimed to characterize orthostatic intolerance in CFS and to study the effects of exercise on OI.

Methods

CFS (n = 39) and control (n = 25) subjects had recumbent and standing symptoms assessed using the 20-point, anchored, ordinal Gracely Box Scale before and after submaximal exercise. The change in heart rate (ΔHR ≥ 30 bpm) identified Postural Orthostatic Tachycardia Syndrome (POTS) before and after exercise, and the transient, exercise-induced postural tachycardia Stress Test Activated Reversible Tachycardia (START) phenotype only after exercise.

Results

Dizziness and lightheadedness were found in 41% of recumbent CFS subjects and in 72% of standing CFS

SUBMITTER: Garner R 

PROVIDER: S-EPMC6547462 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature