Trait ontology analysis based on association mapping studies bridges the gap between crop genomics and Phenomics.

ABSTRACT:

Background

Trait ontology (TO) analysis is a powerful system for functional annotation and enrichment analysis of genes. However, given the complexity of the molecular mechanisms underlying phenomes, only a few hundred gene-to-TO relationships in plants have been elucidated to date, limiting the pace of research in this "big data" era.

Results

Here, we curated all the available trait associated sites (TAS) information from 79 association mapping studies of maize (Zea mays L.) and rice (Oryza sativa L.) lines with diverse genetic backgrounds and built a large-scale TAS-derived TO system for functional annotation of genes in various crops. Our TO system contains information for up to 18,042 genes (6345 in maize at the 25 k level and 11,697 in rice at the 50 k level), including

SUBMITTER: Pan Q 

PROVIDER: S-EPMC6547493 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature