Is FMR1 CGG repeat length a predictor of in vitro fertilization stimulation response or outcome?

ABSTRACT:

Objective

To study a broad range of FMR1 CGG repeat lengths and assisted reproduction technology (ART) outcomes.

Design

Retrospective cohort study.

Setting

Private ART practice.

Patient(s)

Fresh autologous ART stimulation cycles.

Intervention(s)

None.

Main outcome measure(s)

Oocyte yield, live birth.

Result(s)

We screened 14,088 fresh autologous ART cycles from 2012 to 2015, of which 4,690 cycles in 3,290 patients met the inclusion criteria. The FMR1 repeat length was statistically significantly but weakly associated with oocyte yield and other markers of ovarian response. The receiver operating characteristic curve analysis suggested extremely limited predictive ability. Moreover, the FMR1 repeat length was not statistically significantly

SUBMITTER: Banks N 

PROVIDER: S-EPMC6548191 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature