Cognitive outcomes following coronary artery bypass grafting: A systematic review and meta-analysis of 91,829 patients.

ABSTRACT:

Background

Cognitive impairments, including delirium, are common after coronary artery bypass grafting (CABG) surgery, as described in over three decades of research. Our aim was to pool estimates across the literature for the first-time, relative to time (from pre- to post-CABG) and diagnosis (cognitive impairment, delirium and dementia).

Methods

A systematic search of four databases was undertaken. 215 studies incorporating data from 91,829 patients were used to estimate the prevalence of cognitive impairments pre- and post-CABG, including delirium and dementia post-CABG, using random effects meta-analyses.

Results

Pre-surgical cognitive impairment was seen in 19% of patients. Post-operatively, cognitive impairment was seen in around 43% of patients acutely; this re

SUBMITTER: Greaves D 

PROVIDER: S-EPMC6548308 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature