Providence virus: An animal virus that replicates in plants or a plant virus that infects and replicates in animal cells?

ABSTRACT:

Introduction

Emerging viral diseases, most of which are zoonotic, pose a significant threat to global health. There is a critical need to identify potential new viral pathogens and the challenge is to identify the reservoirs from which these viruses might emerge. Deep sequencing of invertebrate transcriptomes has revealed a plethora of viruses, many of which represent novel lineages representing both plant and animal viruses and little is known about the potential threat that these viruses pose.

Methods

Providence virus, an insect virus, was used to establish a productive infection in Vigna unguiculata (cowpea) plants. Providence virus particles purified from these cowpea plants were used to infect two mammalian cell lines.

Findings

Here, we present evidence that Prov

SUBMITTER: Jiwaji M 

PROVIDER: S-EPMC6548363 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature