Associations of General and Central Adiposity With Incident Diabetes in Chinese Men and Women.

ABSTRACT:

Objective

We assess associations of general and central adiposity in middle age and of young adulthood adiposity with incident diabetes in adult Chinese and estimate the associated population burden of diabetes.

Research design and methods

The prospective China Kadoorie Biobank enrolled 512,891 adults 30-79 years of age from 10 localities across China during 2004-2008. During 9.2 years of follow-up, 13,416 cases of diabetes were recorded among 482,589 participants without diabetes at baseline. Cox regression yielded adjusted hazard ratios (HRs) for incident diabetes associated with measures of general (e.g., BMI and BMI at 25 years) and central (e.g., waist circumference [WC]) adiposity.

Results

The mean (SD) BMI was 23.6 kg/m² (3.4 kg/m²), and 3

SUBMITTER: Bragg F 

PROVIDER: S-EPMC6548563 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature