Gesturing tool use and tool transport actions modulates inferior parietal functional connectivity with the dorsal and ventral object processing pathways.

ABSTRACT: Interacting with manipulable objects (tools) requires the integration of diverse computations supported by anatomically remote regions. Previous functional neuroimaging research has demonstrated the left supramarginal (SMG) exhibits functional connectivity to both ventral and dorsal pathways, supporting the integration of ventrally-mediated tool properties and conceptual knowledge with dorsally-computed volumetric and structural representations of tools. This architecture affords us the opportunity to test whether interactions between the left SMG, ventral visual pathway, and dorsal visual pathway are differentially modulated when participants plan and generate tool-directed gestures emphasizing functional manipulation (tool use gesturing) or structure-based grasping (tool transport gestur

SUBMITTER: Garcea FE 

PROVIDER: S-EPMC6548598 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature