The spatial chronnectome reveals a dynamic interplay between functional segregation and integration.

ABSTRACT: The brain is highly dynamic, reorganizing its activity at different interacting spatial and temporal scales, including variation within and between brain networks. The chronnectome is a model of the brain in which nodal activity and connectivity patterns change in fundamental and recurring ways over time. Most literature assumes fixed spatial nodes/networks, ignoring the possibility that spatial nodes/networks may vary in time. Here, we introduce an approach to calculate a spatially fluid chronnectome (called the spatial chronnectome for clarity), which focuses on the variations of networks coupling at the voxel level, and identify a novel set of spatially dynamic features. Results reveal transient spatially fluid interactions between intra- and internetwork relationships in which brain ne

SUBMITTER: Iraji A 

PROVIDER: S-EPMC6548674 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature