Eimeria maxima-induced transcriptional changes in the cecal mucosa of broiler chickens.

ABSTRACT:

Background

Apicomplexan protozoans of the genus Eimeria cause coccidiosis, one of the most economically relevant parasitic diseases in chickens. The lack of a complete understanding of molecular mechanisms in the host-parasite interaction limits the development of effective control measures. In the present study, RNA sequencing (RNA-Seq) was applied to investigate the host mRNA profiles of the cecal mucosa collected at day 5 post-infection with Eimeria maxima (EM).

Results

Total RNA from cecal samples of the uninfected naïve control and the EM groups was used to make libraries, generating 354,924,372 and 356,229,250 usable reads, respectively, which were assembled into a total of 386,088 high-quality unigenes (transcripts) in Trinity software. RNA-Seq analysis of cecal sampl

SUBMITTER: Li C 

PROVIDER: S-EPMC6549307 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature