Trends in the risk of cardiovascular disease in women with breast cancer in a Dutch nationwide cohort study.

ABSTRACT:

Objectives

To investigate trends in cardiovascular disease (CVD) risk following breast cancer using national registry data.

Methods

A nationwide cohort study was conducted, comprising 163 881 women with in situ (7.6%) or invasive (92.4%) breast cancer and women of the general population, ranging from 3 661 141 in 1996 to 4 566 573 in 2010. CVD mortality rate in women with and without breast cancer and hospitalisation rate after breast cancer were calculated for the years 1996-2010. Age-adjusted CVD and breast cancer mortality within 5 years after breast cancer admission (1997-2010) were compared with 1996 calculated with a Cox proportional hazard analysis.

Results

The absolute 10-year CVD mortality risk following breast cancer decreased from 56 per 1000 women in 1996

SUBMITTER: Buddeke J 

PROVIDER: S-EPMC6549609 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature