Prognostic model for traumatic death due to bleeding: cross-sectional international study.

ABSTRACT:

Objective

To develop and validate a prognostic model and a simple model to predict death due to bleeding in trauma patients.

Design

Cross-sectional study with multivariable logistic regression using data from two large trauma cohorts.

Setting

274 hospitals from 40 countries in the Clinical Randomisation of Anti-fibrinolytic in Significant Haemorrhage (CRASH-2) trial and 24 hospitals in the Northern French Alps Trauma registry.

Participants

13 485 trauma patients in the CRASH-2 trial and 9945 patients in the Northern French Alps Trauma registry who were admitted to hospital within 3 hours of injury.

Main outcome measure

In-hospital death due to bleeding within 28 days.

Results

There were 815 (6%) deaths from bleeding in the CRASH-2 trial and 102 (1

SUBMITTER: Ageron FX 

PROVIDER: S-EPMC6549712 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature