Pathobiological features favouring the intercontinental dissemination of highly pathogenic avian influenza virus.

ABSTRACT: Avian influenza viruses (AIVs) are a continued threat to global health and economy. Unlike other highly pathogenic AIVs, novel H5N8 disseminated very quickly from Korea to other areas in Asia, Europe and even North America following its first outbreak in 2014. However, the pathobiological features of the virus that favoured its global translocation remain unknown. In this study, we used a compartmental model to examine the avian epidemiological characteristics that would support the geographical spread of influenza by bird migration, and to provide recommendations for AIV surveillance in wild bird populations. We simulated virus transmission and translocation in a migratory bird population while varying four system properties: (i) contact transmission rate; (ii) infection recovery rate; (i

SUBMITTER: Li X 

PROVIDER: S-EPMC6549942 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature