Exposure to Fine Particulate Matter and Ovarian Reserve Among Women from a Fertility Clinic.

ABSTRACT:

Background

An increasing number of studies have linked air pollution to decreased fertility. Whether this is due to an effect on ovarian reserve is unknown.

Method

Our study included 632 women attending the Massachusetts General Hospital Fertility Center (2004-2015) who had a measured antral follicle count. Validated spatiotemporal models estimated daily particulate matter <2.5 µg/m (PM2.5) (based on residential address) for the 3 months before the antral follicle count. We analyzed associations with Poisson regression.

Results

Every 2 µg/m increase in estimated PM2.5 exposure was associated with a -7.2% (95% confidence interval = -10.4%, -3.8%) lower antral follicle count adjusting for age, body mass index, smoking status, and year and season of the count. The associ

SUBMITTER: Gaskins AJ 

PROVIDER: S-EPMC6550330 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature