Leptospirosis as a risk factor for chronic kidney disease: A systematic review of observational studies.

ABSTRACT:

Background

Leptospirosis is a worldwide prevalent zoonosis and chronic kidney disease (CKD) is a leading global disease burden. Because of pathophysiological changes in the kidney, it has been suggested that these conditions may be associated. However, the extent of this interaction has not been synthetized. We aimed to systematically review and critically appraise the evidence on the association between leptospirosis and CKD.

Methodology/principal findings

Observational studies with a control group were selected. Leptospirosis, confirmed with laboratory methods, and CKD also based on a laboratory assessment, were the exposures and outcomes of interest. The search was conducted in EMBASE, MEDLINE, Global Health, Scopus and Web of Science. Studies selected for qualitative syn

SUBMITTER: Carrillo-Larco RM 

PROVIDER: S-EPMC6550415 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature