MON-439 Evaluation of Surgical Resection Goal and Its Relationship to the Extent of Resection and Patient Outcomes in 221 Patients following Transsphenoidal Surgery for Nonfunctioning Pituitary Adenomas: Data from the TRANSSPHER Study

ABSTRACT: Abstract Background: Prospective data of the influence of the neurosurgeon’s preoperative goal regarding the extent of tumor resection and patient outcomes are scarce in patients with pituitary adenomas who have undergone transsphenoidal pituitary surgery using modern gland-sparing surgical techniques. Objective: We analyze the relationship between surgical tumor removal goal and patient outcomes in a prospective multicenter study of patients with nonfunctioning pituitary adenomas (ClinicalTrials.gov NCT02357498). Methods: Centrally adjudicated extent of tumor resection (gross total resection [GTR] and subtotal resection [STR]) data were analyzed using standard univariate and multivariable analyses. Results: A total of 221 patients were treated with transsphenoidal surgery at 7 pituitary c

SUBMITTER: Little A 

PROVIDER: S-EPMC6551158 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature