RiboStreamR: a web application for quality control, analysis, and visualization of Ribo-seq data.

ABSTRACT:

Background

Ribo-seq is a popular technique for studying translation and its regulation. A Ribo-seq experiment produces a snap-shot of the location and abundance of actively translating ribosomes within a cell's transcriptome. In practice, Ribo-seq data analysis can be sensitive to quality issues such as read length variation, low read periodicities, and contaminations with ribosomal and transfer RNA. Various software tools for data preprocessing, quality assessment, analysis, and visualization of Ribo-seq data have been developed. However, many of these tools require considerable practical knowledge of software applications, and often multiple different tools have to be used in combination with each other.

Results

We present riboStreamR, a comprehensive Ribo-seq quality cont

SUBMITTER: Perkins P 

PROVIDER: S-EPMC6551240 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature