Neutrophil-to-lymphocyte ratio (NLR) fails to predict outcome of diffuse large B cell lymphoma.

ABSTRACT:

Background

Neutrophil-to-lymphocyte ratio (NLR) has been recognized as a poor prognostic indicator in various solid tumors.

Methods

We retrospectively analyzed 530 patients with de novo DLBCL who were diagnosed from April 2002 to November 2017.

Results

The median age of patients was 69 (range, 20-95) years, and 59% were male. The optimal cutoff for NLR was 5.2. NLR (5.2) was not associated with overall and progression free survival.

Conclusion

Our study failed to reveal the predictive value of NLR and demonstrated that the NCCN-IPI might be the most powerful predictor in DLBCL.

SUBMITTER: Azuma Y 

PROVIDER: S-EPMC6551461 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature